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health care workers wearing personal protective equipment "In addition, covered employers must ensure 6 feet of distance between workers. In situations where this is not possible, employers should erect barriers between employees where feasible." Covered employers also must provide workers with paid time off to get vaccinated and recover from side effects. Employees who test positive for the coronavirus or could be contagious must work remotely or separately from other workers or be provided paid time off (up to $1,400 a week). Tax credits under the American Rescue Plan may cover paid time off for employers with fewer than 500 employees. Notably, under the ETS, fully vaccinated workers do not have to wear masks, keep physically distant or use barriers "when in well-defined areas where there is no reasonable expectation that any person will be present with suspected or confirmed coronavirus." Pierce Blue, an attorney with Morgan Lewis in Washington, D.C., said the standard imposes a number of new requirements on health care employers that they should carefully follow. "It is important to note, however, that the standard does not apply to all workspaces in the health care sector. Employers should carefully review the standard to determine where it applies and where it does not." Logsdon observed that many health care employers already have been practicing most of the ETS requirements. However, some of the rules may require employers to adjust their policies or take additional steps. The ETS appears to be very consistent with existing OSHA guidance on COVID-19 workplace safety, Deffebach noted, but the new mandate may give OSHA "greater enforcement teeth" than under the Occupational Safety and Health Act's general duty clause, which requires employers to provide a work environment that is "free from recognized hazards that are causing or are likely to cause death or serious physical harm." "OSHA is increasing its resources, particularly in enforcement, and is encouraging in-person inspections," observed Courtney Malveaux, an attorney with Jackson Lewis in Richmond, Va. Apart from employers who work as contractors in health care settings, the new standard means very little for other employers, Malveaux explained. "The more significant story for non-health care employers is the new guidance that OSHA published … particularly as it relates to vaccinated and unvaccinated individuals in the workplace." Most employers that are not covered by the ETS or involved with public transportation "no longer need to take steps to protect their fully vaccinated workers who are not otherwise at-risk from COVID-19 exposure," except when measures are "required by federal, state, local, tribal, or territorial laws, rules, and regulations," according to OSHA. "Fully vaccinated" means two weeks have passed since the employee received the final dose of a vaccine authorized by the U.S. Food and Drug Administration. Employers need to continue taking steps to protect unvaccinated and otherwise at-risk workers who may have a weakened response to the vaccine. Identify opportunities to get vaccinated. Properly wear a face mask that covers the nose and mouth. Stay at least 6 feet away from other people. Be aware of whether rooms are properly ventilated. Practice good personal hygiene and wash hands often. Employers can help reduce the spread of COVID-19, according to OSHA, by: Offering paid time off for employees to get vaccinated.

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Engrail Therapeutics Extends Series A Financing to $64 Million Proceeds to Support Advancement of Diverse Neuroscience Pipeline, Including Ongoing Execution of ENX-101 and ENX-102 Phase 1 Studies August 03, 2021 08:00 AM Eastern Daylight Time SAN DIEGO--( BUSINESS WIRE )--Engrail Therapeutics™ (Engrail) (the Company), a neuroscience company focused on the acquisition, development and commercialization of patient-centric therapies, today announced the close of a $32 million extension of its Series A financing round, which brings the total round to $64 million. Nan Fung Life Sciences (NFLS), the global investment platform of the Nan Fung Group, led this round following their leadership of the original Series A raise. The Company will use the proceeds to finance the advancement of their diverse pipeline, including its lead assets, ENX-101, ENX-102 and internal preclinical programs. Engrail’s lead compounds are subtype-selective GABA-A modulators with compelling pharmacological profiles that possess wide ranging therapeutic utility. “Earlier this year, we initiated a Phase 1b study for ENX-101 and Phase 1a study for ENX-102. This funding will help advance these assets, as well as our earlier-stage pipeline, as rapidly as possible while continuing to build out our clinical development capabilities,” said Vikram Sudarsan, Ph.D., CEO and president of Engrail Therapeutics. “Additionally, NFLS has made a long-term commitment to invest $2 billion in the life sciences sector, enabling us to continue leveraging our flexible transaction model to acquire assets with validated mechanisms to treat diseases of the nervous system through licensing, co-development and company acquisitions. We continue to pursue transactions that will grow our pipeline and cater to major unmet needs in the neurosciences.” Engrail has assembled a diverse portfolio of assets with validated mechanisms through its dynamic model for advancing drugs aimed at treating life-limiting diseases of the nervous system. By adopting a 'science-first' approach, combined with a comprehensive view of clinical development strategy, regulatory considerations and intellectual property, the Company can find differentiated assets with validated mechanisms of action for diseases where significant patient need still exists. “Engrail has demonstrated impressive progress in the past year since its founding with the initiation of two Phase 1 studies for its lead candidates,” said Peter Bisgaard, managing director of NFLS and chairman of Engrail’s board of directors. “We are excited to support this team as it continues acquiring high-quality assets and advances them through clinical development.” Founded in 2019, Engrail is forging a new direction to reduce the enormous burden of diseases that impact the nervous system. We unite biological insights with clinically meaningful solutions to build and catalyze a diversified portfolio of transformative medicines. Harnessing our rigorous scientific approach to identify the most promising therapies, we leverage our flexible transaction model to advance assets with validated mechanisms and efficiently move them through development to commercialization. Engrail is supported by a long-term more about the author capital commitment from Nan Fung Life Sciences . For more information, visit . Nan Fung Life Sciences is a global life sciences investment platform with a long-term capital commitment from the Nan Fung Group. Our team possesses diverse experience with long track records in company formation, venture capital, growth/buyout investments, and drug discovery and development. Through direct investments via Pivotal bioVenture Partners US and Pivotal bioVenture Partners China as well as fund investments, we cover the full spectrum of the life sciences industry including therapeutics, medical devices and diagnostics and across all development stages. To learn more, visit .